{"id":58949,"date":"2025-02-13T18:00:08","date_gmt":"2025-02-13T18:00:08","guid":{"rendered":"https:\/\/cdhf.staging.not4prod.com\/?p=58949"},"modified":"2025-02-18T14:09:36","modified_gmt":"2025-02-18T14:09:36","slug":"infliximab-for-the-treatment-of-inflammatory-bowel-disease-an-overview-of-drug-history-and-delivery","status":"publish","type":"post","link":"https:\/\/cdhf.ca\/en\/infliximab-for-the-treatment-of-inflammatory-bowel-disease-an-overview-of-drug-history-and-delivery\/","title":{"rendered":"Infliximab for the Treatment of Inflammatory Bowel Disease: An Overview of Drug History and Delivery"},"content":{"rendered":"\n

What is Infliximab and where did it come from? <\/strong> <\/h2>\n\n\n\n

Infliximab is a medication used to treat inflammatory bowel disease (IBD<\/a>), including both Crohn’s disease and ulcerative colitis.\u202fThe initial formulation of infliximab known as Remicade\u00e2<\/sup> has been used for over twenty years, gaining approval in Canada for the treatment of Crohn\u2019s disease in 2001 and Ulcerative Colitis in 20061<\/sup>. With its longstanding use, infliximab is well studied and known to be effective at achieving and maintaining control of IBD, allowing patients to feel better and stay better for a long time while decreasing their need for surgery2-4<\/sup>. In addition to treating inflammation in the bowel, infliximab is effective at treating fistulas, which are abnormal connections between the intestines and the skin or other organs5<\/sup>. <\/p>\n\n\n\n

Infliximab is also known to be effective at treating extra-intestinal manifestations of IBD including skin changes, and inflammation in the eyes and joints6<\/sup>. Over the years, many studies have looked at the long-term safety of infliximab.\u202fThese studies found that while it is generally safe, it can cause some side effects including infections and allergic reactions. These side effects are rare, and risk can be reduced with proper preventative measures7<\/sup>.  <\/p>\n\n\n\n

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