- Dyspepsia is an umbrella term used to describe persistent pain or burning sensation in the upper middle part of the stomach, feeling of abdominal fullness and early satiety.
- Possible undelying causes of dyspepsia include peptic ulcer disease, H. pylori infection, gastroparesis, gatroesophageal cancer, pancreatitis, pancreatic cancer and Crohn’s disease. As well, more than 70% of patients have « functional dyspepsia », where there is the exclusion of a structural gastrointestinal disease. (Talley et al. 2015)
- About a fifth of people are affected at some point in their lives, however most people do not seek medical care. (Ford et al. 2013)
- Recognition of dyspepsia is poor. Globally, dyspepsia is uninvestigated in about 20% of cases. (Ford et al. 2015)
- While dyspepsia does not affect survival, it is responsible for substantial quality of life impairment and health care costs.
Ford AC and Moayyedi P. Dyspepsia. BMJ. 2013 Aug 29;347:f5059.
Ford AC et al. Global prevalence of, and risk factors for, uninvestigated dyspepsia: A meta-analysis. Gut. 2015 Jul;64(7):1049-57.\
Talley NJ and Ford AC. Functional dyspepsia. N Engl J Med. 2015 Nov 5;373(19):1853-63.