Image of a women in stomach discomfort

The Mind-Gut Connection: How to Reset Your Nervous System During Digestive Flare-Ups

Amber Cohen, PsyD, CPsych

Written by: Amber Cohen, PsyD, CPsych

Updated: August 10th, 2026

Digestive flare-ups may feel intense. Symptoms can include cramping, stomach pain, bloating, diarrhea, and nausea, which can all feel more intense during stressful periods. Although one’s food intake and diet contribute to an individual’s digestive health, we tend to overlook the fact that the nervous system may influence digestive system functions.  

Research suggests that anxiety and stress may influence digestion through the gut-brain axis. This network provides the brain and digestive system access to communicate through signals to one another. Thus, creating a two-way relationship in which emotions may impact digestive functions, while those functions impact one’s emotional well-being.  

Therefore, understanding the underlying factors that impact the digestive system and how to calm the nervous system during those digestive flare-ups may allow individuals to gain higher insight and control over their physical, as well as psychological, health.   

Stress may influence digestive flare-ups

During periods of stress, the sympathetic nervous system is activated; thus, individuals may feel the “fight or flight” response that is created. Therefore, instead of the body focusing on its digestive system, it puts its energy into surviving and balancing the current stress response. Which may help explain why the digestive system slows down, and individuals may experience symptoms that include: 

Stress may also contribute to digestive flare-ups for individuals who experience IBS. However, these stressors may not always seem intense; they can include poor sleep schedules, anxiety, everyday demands, lack of emotional support and more.  

As a result, prolonged stress may lead to slower digestive processing, the gut reacting to greater amounts of triggers and causing overreactions, simply because the nervous system is stuck at a high level of activation. Thus, creating a significant point in understanding how to calm digestive flare-ups, to regulate both the nervous system and the digestive system.   

Nervous system rest techniques for the digestive system

Digestion is normally supported and controlled by the parasympathetic nervous system because it helps with the “rest and digest” process. However, when experiencing stress, the body focuses on the “fight or flight” response, and digestion slows down, which reduces the body’s “rest and digest” process. Therefore, it is important to bring the body back to equilibrium rather than staying in the “fight or flight” response during periods of stress.  

To reset and control the body during that response, performing small practices throughout the day can create significant changes in an individual’s stress response and digestive system. 

These practices may include:  

Although the practices may seem simple, research shows they provide support for the body. They promote relaxation to the body’s nervous system and help balance the digestive system, as well as reduce digestive flare-ups.  

Vagal breathing for digestion 

Vagal breathing focuses on stimulating an individual’s vagus nerve through controlled and slow-paced breathing. The vagus nerve plays a key role in carrying those significant signals to your heart, brain and digestive system within the parasympathetic nervous system. Therefore, research shows that using slow and steady vagal breathing may activate the body’s relaxation response. 

The main vagal breathing exercise may include: 

Breathing exercises may not reduce your overall stress level, but they can help with negative digestive functions and digestive flare-ups caused by stressors.  

Grounding techniques for IBS

The main idea in using grounding techniques is to turn the brain’s attention away from stressors, anxious thoughts or emotions, and malaise. This is done through the techniques focusing on the present rather than fixating on the past or future, possibly reducing tension in the nervous system.  

Grounding techniques include: 

Practicing grounding techniques for IBS helps individuals progress positively in relaxation methods and provides attention to certain symptoms that may need it.      

How individuals can calm an overactive gut

To completely calm an overactive gut, one must provide attention to both the nervous and digestive systems simultaneously. This attention and support does not need to be drastic; it can be simple daily habits that progress the body’s relaxation response. 

These simple daily habits may include: 

Every individual’s health and digestive symptoms differ. Therefore, different techniques work for different individuals, as digestive symptoms may not be as intense or chronic for every person. It is a significant aspect to not only practice small habits to minimize an overactive gut, but also to visit a healthcare professional, which will allow one to gain more insight and support on their digestive health.  

Overall, by understanding that the mind-gut connection provides a strong communication line between the nervous and digestive system, it has created positive progress in not solely focusing on digestive relaxation techniques, but it also includes calming down the nervous system simultaneously.  

Stressors may cause digestive flare-ups, overactive and sensitive guts for individuals with IBS and heightened nervous systems. However, using techniques such as nervous system reset relaxation practices, grounding techniques, and simple daily habits that can reduce an overactive gut can support individuals.

References  

  1. Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018). Vagus nerve as modulator of the brain-gut axis in psychiatric and inflammatory disorders. Frontiers in Psychiatry, 9, 44. https://pubmed.ncbi.nlm.nih.gov/29593576
  2. Cherpak, C. E. (2019). Mindful eating: A review of how the stress-digestion-mindfulness triad may modulate and improve gastrointestinal and digestive function. Integrative Medicine (Encinitas), 18(4), 48-53. https://pmc.ncbi.nlm.nih.gov/articles/PMC7219460
  3. Harvard Health Publishing. (2024, May 4). Relaxation therapy for gut health. Harvard Health. https://www.health.harvard.edu/healthbeat/relaxation-therapy-for-gut-health
  4. International Foundation for Gastrointestinal Disorders. (n.d.). Relaxation techniques to manage IBS symptoms. IFFGD. https://aboutibs.org/treatment/psychological-treatments/relaxation-techniques-for-ibs/  
  5. Konturek, P. C., Brzozowski, T., & Konturek, S. J. (2011). Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. Journal of Physiology and Pharmacology, 62(6), 591-599. https://pubmed.ncbi.nlm.nih.gov/22314561/  
  6. Laborde, S., Hosang, T., Mosley, E., & Dosseville, F. (2019). Influence of a 30-day slow-paced breathing intervention compared to social media use on subjective sleep quality and cardiac vagal activity. Journal of Clinical Medicine, 8(2), 193. https://pmc.ncbi.nlm.nih.gov/articles/PMC6406675/  
  7. Leigh, S. J., Uhlig, F., Wilmes, L., Sanchez-Diaz, P., Gheorghe, C. E., Goodson, M. S., Kelley-Loughnane, N., Hyland, N. P., Cryan, J. F., & Clarke, G. (2023). The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota-gut-brain axis perspective. The Journal of Physiology, 601(20), 4491-4538. https://pubmed.ncbi.nlm.nih.gov/37756251
  8. Mayer, E. A. (2011). Gut feelings: the emerging biology of gut-brain communication. Nature Reviews Neuroscience, 12(8), 453-466. https://pmc.ncbi.nlm.nih.gov/articles/PMC3845678/ 
  9. Mayo Clinic Staff. (2024, October 11). Irritable bowel syndrome. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/diagnosis-treatment/drc-20360064
  10. Moryś, J., Małecki, A., & Nowacka-Chmielewska, M. (2024). Stress and the gut-brain axis: an inflammatory perspective. Frontiers in Molecular Neuroscience, 17, 1415567. https://pubmed.ncbi.nlm.nih.gov/39092201
  11. Ubie Health. (2026, January 29). How do you calm down an IBS flare-up? Ubie Doctor’s Note. https://ubiehealth.com/doctors-note/calm-ibs-flare-up-fast-soothe-gut-37-methods-guide15e7  

Related Articles:

View all News & Articles

Image of a woman in stomach discomfort

The Mind-Gut Connection: How Mindfulness Helps Manage Chronic Digestive Conditions

Image of a women in stomach discomfort

The Mind-Gut Connection: How to Reset Your Nervous System During Digestive Flare-Ups

Image of a stomach to connect to mind-gut connection

​​The Mind-Gut Connection: Why Anxiety Shows Up in Your Stomach First​​​ 

Feeding Your Mind and Gut: Enhancing Your Second Brain for Improved Health 

girl holding stomach and head, anxious and stomach ache

Gut Health and Mental Health: Alleviating Anxiety Symptoms

man listening to gut-directed hypnotherapy

Gut-Directed Hypnotherapy for IBS: A Dietitian’s Comparative Review of Nerva and Regulora Experiences

meditation and yoga banner

Mindfulness, Yoga and the Gut-Brain Connection

Tips for Mind-Body Wellness: Trending Now Presentation

blue brains on pink background

The Connection Between Gut, Mood and Behaviour

woman holding her temples due to stress

IBS and Stress: Is There a Link?

girl on computer for Cognitive behavioural therapy

Cognitive Behavioural Therapy (CBT) for IBS

human brain model in hands, top view

How Stress Impacts The Gut & How to Manage

Meditation for Mind Gut Connection

Webinar: Mind-Gut Connections for Digestive Disorders

Women looking at skin in mirror

How Does Your Gut Health Affect Your Skin?

yoga class

The Importance of Managing Stress for People who Suffer from IBS

Women talking to another women in an office with a lot of windows

Mental Health, IBS and Removing the Stigma

Hands on top of other hands supporting one another

IBS, IBD & Mental Health Webinar

Women laughing in yoga pose

Wait… My Gut Affects My Mental Health?

Bowl of healthy salad and tofu

Mental Health and Nutrition

Beer bottles being held in the air

COVID-19 and Alcohol: Am I drinking too much?

Black man pondering with yellow background

Ways our Mind and Gut are Connected