New Bausch Health treatment UCERIS® (budesonide) aerosol foam now available across Canada to treat mild to moderate distal ulcerative colitis in adults 

CDHF

Written by: CDHF

Updated: October 31st, 2023

LAVAL, Quebec, September 12, 2023 – Bausch Health Companies Inc. (NYSE/TSX: BHC) is pleased to announce that following its approval by Health Canada the new treatment PrUCERIS® (budesonide) aerosol foam is now available across Canada to treat mild to moderate distal ulcerative colitis in adults. 

UCERIS is the only glucocorticosteroid rectal foam available in Canada indicated for the induction of remission in adult patients with active mild to moderate distal ulcerative colitis extending up to 40 cm from the anal verge.1 In a study comparing budesonide foam and budesonide enema in patients with active distal ulcerative colitis, most patients (84%) preferred the foam formulation because of its better tolerability and easier application.2 

“Bausch Health is pleased to make this new treatment for ulcerative colitis available to Canadians, providing an innovative therapy option using a convenient aerosol foam,” said Cees Heiman, Senior Vice-President, Europe and Canada, Bausch Health. “This is part of our commitment to being a trusted partner in the healthcare of Canadians.” 

Ulcerative colitis is a chronic disease affecting the large intestine, or colon. The condition causes inflammation and ulceration (sores) along the lining of the colon, which can lead to abdominal pain, cramps, bleeding and diarrhea.3 In ulcerative colitis, the inflammation starts at the rectum and continues through the colon. Symptoms include diarrhea with blood and mucus, pain on the left-hand side of the abdomen, urgency and tenesmus (the feeling of needing to pass stools even if the bowel is empty).

“Distal ulcerative colitis can be challenging for patients to live with and gastroenterologists to treat. Our goal is to put the disease into remission so that patients can improve their quality of life,” said Dr. Brian Bressler, Founder of The IBD Centre of BC in Vancouver and Clinical Associate Professor of Medicine in the Division of Gastroenterology at the University of British Columbia. “UCERIS can help overcome current treatment limitations by reaching the affected area of the distal colon and keeping the medication there long enough to be effective. People suffering from distal ulcerative colitis will have another option to consider when facing this disease.” 

“Living with ulcerative colitis can mean painful, frequent and, at times, bloody stools.” said Gail Attara, president and chief executive officer of the Gastrointestinal Society, a patient group known by its badgut.org website. “We look forward to this product being widely available for individuals living with ulcerative colitis who need a good treatment option that is easy to use, which targets the disease directly. UCERIS is an effective solution, meeting the disease right where it happens.” 

UCERIS is available in one strength: 2 mg budesonide per metered dose and is applied starting twice a day for two weeks followed by once a day for the next four weeks.4 

In the two clinical studies on which the approval of UCERIS rectal aerosol foam was based, a significantly higher proportion of patients in the UCERIS group than in the placebo group were in remission at Week 6 (38.3% and 44.0% vs. 25.8% and 22.4% respectively, pooled p<0.0001) and had a rectal bleeding sub-score of 0 at Week 6 (46.6% and 50.0% vs. 28.0% and 28.6% respectively, pooled p<0.0001). There was also a higher proportion of patients in the UCERIS group than in the placebo group with an endoscopy sub-score of 0 or 1 at Week 6 (55.6% and 56.0% vs. 43.2% and 36.7% respectively.5 

About Bausch Health 

Bausch Health logo

Bausch Health Companies Inc. (NYSE/TSX: BHC) is a global diversified pharmaceutical company whose mission is to improve people’s lives with our healthcare products. We develop, manufacture and market a range of products primarily in gastroenterology, hepatology, neurology, dermatology, international pharmaceuticals and eye health, through our controlling ownership interest in Bausch + Lomb Corporation. With our leading durable brands, we are delivering on our commitments as we build an innovative company dedicated to advancing global health. For more information, visit www.bauschhealth.com.

Bausch Health, Canada Inc.’s prescription treatment portfolio is focused on dermatology, gastrointestinal and cardio-metabolic conditions. Bausch Health also has two manufacturing facilities for prescription pharmaceuticals in Canada: in Laval, Quebec, and Steinbach, Manitoba. More information can be found at the Company’s website at www.bauschhealth.ca.

References

1. Bausch Health, Canada Inc., UCERIS rectal foam Product Monograph, https://bauschhealth.ca/wp-content/uploads/2022/06/Uceris-PM-E-2020-04-15.pdf 

2. Gross V, et al, Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis, Aliment Pharmacol Ther. 2006;23(2):303-312 

3. IBD Clinic, University of Alberta: http://www.ibdclinic.ca/what-is-ibd/ulcerative-colitis/ 

4. Bausch Health, Canada Inc., UCERIS rectal foam Product Monograph, p. 4 and 16, https://bauschhealth.ca/wp-content/uploads/2022/06/Uceris-PM-E-2020-04-15.pdf 

5. Bausch Health, Canada Inc., UCERIS rectal foam Product Monograph, p. 19, https://bauschhealth.ca/wp-content/uploads/2022/06/Uceris-PM-E-2020-04-15.pdf 

Related Articles:

View all News & Articles

ulcerative colitis

Bausch Health, Canada Inc. announces additional public drug plan listings for PrUCERIS® (budesonide) aerosol foam to treat mild to moderate distal ulcerative colitis in adults 

Equity in Nutrition Care Program

IBD Nurses Report on an Ipad

IBD Nurse-Centred Care Impact Report

New Bausch Health treatment UCERIS® (budesonide) aerosol foam now available across Canada to treat mild to moderate distal ulcerative colitis in adults 

November is IBD Awareness Month

ibd and pregnancy cdhf talks with picture of dr. leung

CDHF Talks: IBD and Pregnancy Guidelines

IBD and Pregnancy: Frequently Asked Questions

Toilet paper with smiley face

Is my Poop Healthy/Normal?

woman laying down with hurt stomach

Why Does My Stomach Hurt?

elder man and woman stretching on yoga mats

Exercise and Lifestyle Tips for IBD

Webinar: IBD & Diet

Test tubes of a drug

Switching from a Biologic to a Biosimilar Drug in Canada

Doctor speaking to teenager in office

Transitioning from Pediatric to Adult IBD

Parent shaking hands with doctor with teenager in the background

IBD Transition Checklist for Patients and Parents

young girl holding baby doll

Loeys-Dietz Syndrome and Inflammatory Bowel Disease

CDHF Talks with Dr. Yvette and the CDHF talks logo

CDHF Talks: Understanding the Benefits & Risks of IBD Treatment Options

Mediaplanet: Living with IBD: An Invisible Illness

Children in a classroom raising their hands to answer a question

Blackboards and Bathrooms: A comprehensive resource to help teachers support the education of children with IBD

Women sitting in robe

Spa Day? No thanks, I have a Colonoscopy.

How to Find Functional Foods with Added Probiotics

Women and male bathroom stall

Managing your Digestive Health in the Workplace Webinar

Hands on top of other hands supporting one another

IBS, IBD & Mental Health Webinar

Tornado over someones stomach, holding stomach

Living with Ulcerative Colitis Infographic

Stethoscope on blue background

IBD Treatment Options: Understanding Your Risks and Benefits

Robbie’s Rainbow “You, Me and IBD” Magazine

Stethascope on a blue background

Transition Pathway Brochure for IBD Patients

People sitting on a computer listening to a presentation

Hot off the Presses: The Latest IBD Information from Scientific Meetings Webinar

Webinar: Understanding the Benefits and Risks of IBD Therapies

Preparing for your GI Appointment

Registered dietitian writing in notebook on desk

My Experience with Crohn’s Disease as a RD

Two young boys playing hockey

Pediatric Inflammatory Bowel Disease: Dr. Thomas Walters

Inflammatory Bowel Disease (IBD) with Dr. Mike Evans

IBD Treatment Options- Understanding Your Benefits and Risks Animation

IBD and Pregnancy

CDHF Talks: Dietary Updates and Recommendations for the IBD Patient on a Biosimilar

Uncovering Biologics: Your IBD Bodyguard!

Ulcerative Colitis and Crohn’s Disease: What’s the Difference? Infographic

Fecal Calprotectin: The Inside Story on Inflammation

Teenager sitting outside with headphones on

Living with Crohn’s Disease: Infographic

Taking a photo of food

Diet & Lifestyle Changes for Inflammatory Bowel Disease (IBD)

CDHF Talks: Managing Inflammatory Bowel Disease (IBD) in the Elderly

CDHF Talks: Maintaining a Healthy Weight with IBD

IBD Animation

Switching from a Biologic to a Biosimilar

Teen boy talking to doctor

Biosimilars for IBD: Making the Transition Webinar

Woman in chair reading her laptop and smiling

Biosimilar Library

CDHF Talks: Your New Infusion Clinic

Girl watching ipad

Inflammatory Bowel Disease Digital Toolkit for the Newly Diagnosed

My Life with Ulcerative Colitis

The Timeline of my Ulcerative Colitis Diagnosis

What I Eat in a Day with Ulcerative Colitis

Ulcerative Colitis: My Day to Day with IBD

Let’s Imagine UC Differently

Living Positively with Ulcerative Colitis

Photo of David Mcguire

My First Surgery for Crohn’s Disease: My Life Changed Forever

Man lifting a weight in the gym

5 Sure-Fire Ways to get Bigger, Stronger and Leaner while having IBD: Crohn’s Disease

Notebook with Crohn's disease written on it

Right Hemicolectomy: My Experiences. What’s Next?

Medication on a blue microbe background

IBD Medications during COVID-19

Christmas present

Navigating the Holidays with Inflammatory Bowel Disease (IBD)

Women looking off to the side

Setting Goals to Manage IBD

COVID-19 Vaccines in Immunocompromised Patients with Inflammatory Bowel Disease (IBD)

Covid vaccine

Should IBD patients take the COVID-19 vaccine?

Toilet paper rolling out with a purple background

Why is there Blood in my Stool? Rectal Bleeding

Bear on hospital bed with child

Children with IBD: A Shift in Hospitalization Rates

Yogurt bowl

Inflammatory Bowel Disease and Dietary Patterns

Women looking off to the side with her cell phone in hand

Behaviour Change Strategies

Fecal calprotectin stool test

What is the Fecal Calprotectin Test?

healthy foods

Diet & Lifestyle Changes for Inflammatory Bowel Disease (IBD)

David in the gym looking off to the side

The Psychological effects of IBD: My Crohn’s Story and how I Overcame It

Teenager with his mother

Transitioning from Pediatric to Adult IBD Webinar